PoplarV1, Main, Exploration, bibRecord, 000623

γ-Aminobutyric acid is closely associated with accumulation of flavonoids.

Identifieur interne : 000623 ( Main/Exploration ); précédent : 000622; suivant : 000624

γ-Aminobutyric acid is closely associated with accumulation of flavonoids.

Auteurs : Tiantian Xie [République populaire de Chine] ; Jing Ji [République populaire de Chine] ; Wei Chen [République populaire de Chine] ; Jianyun Yue [République populaire de Chine] ; Changjian Du [République populaire de Chine] ; Jiacheng Sun [République populaire de Chine] ; Lanzhen Chen [République populaire de Chine] ; Zeping Jiang [République populaire de Chine] ; Shengqing Shi [République populaire de Chine]

Source :

Plant signaling & behavior [ 1559-2324 ] ; 2019.

RBID : pubmed:30999791

Descripteurs français

KwdFr :
- Acide gamma-amino-butyrique (métabolisme), Feuilles de plante (effets des médicaments et des substances chimiques), Feuilles de plante (métabolisme), Flavonoïdes (métabolisme), Plant (effets des médicaments et des substances chimiques), Plant (métabolisme), Populus (effets des médicaments et des substances chimiques), Populus (génétique), Populus (métabolisme), Régulation de l'expression des gènes végétaux (effets des médicaments et des substances chimiques), Succinates (pharmacologie), Vigabatrine (pharmacologie), Voies de biosynthèse (effets des médicaments et des substances chimiques).
MESH :
- effets des médicaments et des substances chimiques : Feuilles de plante, Plant, Populus, Régulation de l'expression des gènes végétaux, Voies de biosynthèse.
- génétique : Populus.
- métabolisme : Acide gamma-amino-butyrique, Feuilles de plante, Flavonoïdes, Plant, Populus.
- pharmacologie : Succinates, Vigabatrine.

English descriptors

KwdEn :
- Biosynthetic Pathways (drug effects), Flavonoids (metabolism), Gene Expression Regulation, Plant (drug effects), Plant Leaves (drug effects), Plant Leaves (metabolism), Populus (drug effects), Populus (genetics), Populus (metabolism), Seedlings (drug effects), Seedlings (metabolism), Succinates (pharmacology), Vigabatrin (pharmacology), gamma-Aminobutyric Acid (metabolism).
MESH :
- chemical , metabolism : Flavonoids, gamma-Aminobutyric Acid.
- drug effects : Biosynthetic Pathways, Gene Expression Regulation, Plant, Plant Leaves, Populus, Seedlings.
- genetics : Populus.
- metabolism : Plant Leaves, Populus, Seedlings.
- chemical , pharmacology : Succinates, Vigabatrin.

Abstract

γ-Aminobutyric acid (GABA) is an important neurotransmitter in mammals whose receptor is reported to be regulated by flavonoids. In plants, it is considered to be at the intersection of carbon and nitrogen metabolism, but its relationship with flavonoid metabolism remains unclear. Our recent RNA-seq analysis showed that expression of flavonoid biosynthetic genes was influenced in poplar by the blockage of α-ketoglutarate dehydrogenase (α-KGDH) activity and the application of GABA under NaCl stress, accompanied by the changes in GABA shunt activity. Here, we further found that the flavonoid accumulation was significantly affected by blocking the activities of α-KGDH and GABA transaminase as well as applying exogenous GABA, coupled with the changes of endogenous GABA contents. Key genes involved in the flavonoid biosynthetic pathway were also significantly influenced, including two PALs, 4CL, and two CHSs. Our results suggest that the GABA shunt is closely associated with the metabolism of flavonoids, which would benefit future understanding of GABA's roles in carbon allocation by regulating the pathway of flavonoid biosynthesis under normal or stress conditions.

DOI: 10.1080/15592324.2019.1604015
PubMed: 30999791
PubMed Central: PMC6619973

Affiliations:

République populaire de Chine

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000935
to stream Main, to step Curation: 000935

Le document en format XML

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<series><title level="j">Plant signaling & behavior</title>
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<term>Flavonoids (metabolism)</term>
<term>Gene Expression Regulation, Plant (drug effects)</term>
<term>Plant Leaves (drug effects)</term>
<term>Plant Leaves (metabolism)</term>
<term>Populus (drug effects)</term>
<term>Populus (genetics)</term>
<term>Populus (metabolism)</term>
<term>Seedlings (drug effects)</term>
<term>Seedlings (metabolism)</term>
<term>Succinates (pharmacology)</term>
<term>Vigabatrin (pharmacology)</term>
<term>gamma-Aminobutyric Acid (metabolism)</term>
</keywords>
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<term>Feuilles de plante (effets des médicaments et des substances chimiques)</term>
<term>Feuilles de plante (métabolisme)</term>
<term>Flavonoïdes (métabolisme)</term>
<term>Plant (effets des médicaments et des substances chimiques)</term>
<term>Plant (métabolisme)</term>
<term>Populus (effets des médicaments et des substances chimiques)</term>
<term>Populus (génétique)</term>
<term>Populus (métabolisme)</term>
<term>Régulation de l'expression des gènes végétaux (effets des médicaments et des substances chimiques)</term>
<term>Succinates (pharmacologie)</term>
<term>Vigabatrine (pharmacologie)</term>
<term>Voies de biosynthèse (effets des médicaments et des substances chimiques)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Flavonoids</term>
<term>gamma-Aminobutyric Acid</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Biosynthetic Pathways</term>
<term>Gene Expression Regulation, Plant</term>
<term>Plant Leaves</term>
<term>Populus</term>
<term>Seedlings</term>
</keywords>
<keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Feuilles de plante</term>
<term>Plant</term>
<term>Populus</term>
<term>Régulation de l'expression des gènes végétaux</term>
<term>Voies de biosynthèse</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Populus</term>
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</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Plant Leaves</term>
<term>Populus</term>
<term>Seedlings</term>
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<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Acide gamma-amino-butyrique</term>
<term>Feuilles de plante</term>
<term>Flavonoïdes</term>
<term>Plant</term>
<term>Populus</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Succinates</term>
<term>Vigabatrine</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Succinates</term>
<term>Vigabatrin</term>
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<front><div type="abstract" xml:lang="en">γ-Aminobutyric acid (GABA) is an important neurotransmitter in mammals whose receptor is reported to be regulated by flavonoids. In plants, it is considered to be at the intersection of carbon and nitrogen metabolism, but its relationship with flavonoid metabolism remains unclear. Our recent RNA-seq analysis showed that expression of flavonoid biosynthetic genes was influenced in poplar by the blockage of α-ketoglutarate dehydrogenase (α-KGDH) activity and the application of GABA under NaCl stress, accompanied by the changes in GABA shunt activity. Here, we further found that the flavonoid accumulation was significantly affected by blocking the activities of α-KGDH and GABA transaminase as well as applying exogenous GABA, coupled with the changes of endogenous GABA contents. Key genes involved in the flavonoid biosynthetic pathway were also significantly influenced, including two <i>PALs, 4CL</i>
, and two <i>CHSs</i>
. Our results suggest that the GABA shunt is closely associated with the metabolism of flavonoids, which would benefit future understanding of GABA's roles in carbon allocation by regulating the pathway of flavonoid biosynthesis under normal or stress conditions.</div>
</front>
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<DateCompleted><Year>2020</Year>
<Month>05</Month>
<Day>04</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>05</Month>
<Day>05</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1559-2324</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>14</Volume>
<Issue>7</Issue>
<PubDate><Year>2019</Year>
</PubDate>
</JournalIssue>
<Title>Plant signaling & behavior</Title>
<ISOAbbreviation>Plant Signal Behav</ISOAbbreviation>
</Journal>
<ArticleTitle>γ-Aminobutyric acid is closely associated with accumulation of flavonoids.</ArticleTitle>
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</Pagination>
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<Abstract><AbstractText>γ-Aminobutyric acid (GABA) is an important neurotransmitter in mammals whose receptor is reported to be regulated by flavonoids. In plants, it is considered to be at the intersection of carbon and nitrogen metabolism, but its relationship with flavonoid metabolism remains unclear. Our recent RNA-seq analysis showed that expression of flavonoid biosynthetic genes was influenced in poplar by the blockage of α-ketoglutarate dehydrogenase (α-KGDH) activity and the application of GABA under NaCl stress, accompanied by the changes in GABA shunt activity. Here, we further found that the flavonoid accumulation was significantly affected by blocking the activities of α-KGDH and GABA transaminase as well as applying exogenous GABA, coupled with the changes of endogenous GABA contents. Key genes involved in the flavonoid biosynthetic pathway were also significantly influenced, including two <i>PALs, 4CL</i>
, and two <i>CHSs</i>
. Our results suggest that the GABA shunt is closely associated with the metabolism of flavonoids, which would benefit future understanding of GABA's roles in carbon allocation by regulating the pathway of flavonoid biosynthesis under normal or stress conditions.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Xie</LastName>
<ForeName>Tiantian</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>a State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry , Chinese Academy of Forestry , Beijing , China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ji</LastName>
<ForeName>Jing</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>a State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry , Chinese Academy of Forestry , Beijing , China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Wei</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>a State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry , Chinese Academy of Forestry , Beijing , China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yue</LastName>
<ForeName>Jianyun</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>a State Key Laboratory of Tree Genetics and Breeding, Key Laboratory of Tree Breeding and Cultivation of State Forestry Administration, Research Institute of Forestry , Chinese Academy of Forestry , Beijing , China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Du</LastName>
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<affiliations><list><country><li>République populaire de Chine</li>
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<tree><country name="République populaire de Chine"><noRegion><name sortKey="Xie, Tiantian" sort="Xie, Tiantian" uniqKey="Xie T" first="Tiantian" last="Xie">Tiantian Xie</name>
</noRegion>
<name sortKey="Chen, Lanzhen" sort="Chen, Lanzhen" uniqKey="Chen L" first="Lanzhen" last="Chen">Lanzhen Chen</name>
<name sortKey="Chen, Lanzhen" sort="Chen, Lanzhen" uniqKey="Chen L" first="Lanzhen" last="Chen">Lanzhen Chen</name>
<name sortKey="Chen, Wei" sort="Chen, Wei" uniqKey="Chen W" first="Wei" last="Chen">Wei Chen</name>
<name sortKey="Du, Changjian" sort="Du, Changjian" uniqKey="Du C" first="Changjian" last="Du">Changjian Du</name>
<name sortKey="Ji, Jing" sort="Ji, Jing" uniqKey="Ji J" first="Jing" last="Ji">Jing Ji</name>
<name sortKey="Jiang, Zeping" sort="Jiang, Zeping" uniqKey="Jiang Z" first="Zeping" last="Jiang">Zeping Jiang</name>
<name sortKey="Shi, Shengqing" sort="Shi, Shengqing" uniqKey="Shi S" first="Shengqing" last="Shi">Shengqing Shi</name>
<name sortKey="Sun, Jiacheng" sort="Sun, Jiacheng" uniqKey="Sun J" first="Jiacheng" last="Sun">Jiacheng Sun</name>
<name sortKey="Yue, Jianyun" sort="Yue, Jianyun" uniqKey="Yue J" first="Jianyun" last="Yue">Jianyun Yue</name>
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γ-Aminobutyric acid is closely associated with accumulation of flavonoids.

γ-Aminobutyric acid is closely associated with accumulation of flavonoids.

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